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DCs → antigen presenting cells (APCs): " CD40L induces activation of antigen presenting cells (APCs) such as DCs , monocytes, B-cells and endothelial cells "
antigen presenting cells (APCs) → CD40L: " CD40L induces activation of antigen presenting cells (APCs) such as DCs, monocytes, B-cells and endothelial cells "
IL-12p70 → CD40: " We demonstrate that IFN-? induced Janus kinase 1 (JAK1) enhances CD40 induced IL-12p70 release whilst simultaneously inhibiting IL-10 synthesis, resulting in a pro-inflammatory phenotype of CD40L activated dendritic cells (DCs) "
IL-12p70 → Janus kinase 1 (JAK1): " We demonstrate that IFN-? induced Janus kinase 1 (JAK1) enhances CD40 induced IL-12p70 release whilst simultaneously inhibiting IL-10 synthesis, resulting in a pro-inflammatory phenotype of CD40L activated dendritic cells (DCs) "
IL-12p70 → CD40: " We demonstrate that IFN-? induced Janus kinase 1 (JAK1) enhances CD40 induced IL-12p70 release whilst simultaneously inhibiting IL-10 synthesis, resulting in a pro-inflammatory phenotype of CD40L activated dendritic cells (DCs) "
IL-12p70 → Janus kinase 1 (JAK1): " We demonstrate that IFN-? induced Janus kinase 1 (JAK1) enhances CD40 induced IL-12p70 release whilst simultaneously inhibiting IL-10 synthesis, resulting in a pro-inflammatory phenotype of CD40L activated dendritic cells (DCs) "
IL-12p70 ⊣ Tyk2: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-12p70 ⊣ IL-10: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-10 ⊣ IL-12p70: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-10 ⊣ JAK2: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-12p70 ⊣ Tyk2: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-12p70 → JAK2: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-12p70 → JAK2: " JAK2 mediated enhancing effects on IL-12p70 but did not inhibit IL-10 release, whereas Tyk2 mediated inhibitory effects on IL-12p70 release in this system "
IL-12p70 — IFN-?/JAK: " The mechanism by which complementary IFN-?/JAK activities affect IL-12p70 production involves STAT1 activation and de novo induction of interferon-responsive factors (IRF)-1 and IRF-8 "
IL-12p70 — IFN-?/JAK: " The mechanism by which complementary IFN-?/JAK activities affect IL-12p70 production involves STAT1 activation and de novo induction of interferon-responsive factors (IRF)-1 and IRF-8 "