Hsueh et al., J Steroid Biochem 1985
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This is associated with the ability of GnRH to stimulate plasminogen activator activity in cultured granulosa cells
Wang et al., Mol Cell Endocrinol 1986
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LHRH stimulates plasminogen activator and inhibits steroid production by granulosa cells of adult rat Graafian follicles ... We studied the effects of LHRH and its analogs on plasminogen activator production and progesterone and estradiol secretion by granulosa cells isolated from adult rat Graafian follicles ... LHRH and its agonist ( [ des- -Gly10,D-Trp6,Pro9-NHEt ] LHRH ) stimulated small but significant increases in plasminogen activator production
Wang et al., Endocrinology 1983
:
Both LHRH and the agonist produced a dose related increase in plasminogen activator production