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GP1BB — PLG

Text-mined interactions from Literome

Michelson et al., Blood 1990 : We examined the hypothesis that after plasmin mediated cleavage of platelet surface GPIb , platelets can replenish their surface GPIb pool ... In summary, this study shows that after plasmin mediated cleavage of platelet surface GPIb , platelets can replenish their surface GPIb pool by recruitment of GPIb molecules from the intraplatelet pool ( or from a sequestered surface site )
Adelman et al., Blood 1986 : We have characterized the effects of plasmin on glycoprotein Ib (GpIb) , a platelet membrane receptor for von Willebrand factor (vWF), and on glycocalicin, a fragment of the alpha chain of GpIb that contains the vWF binding region ... These studies indicated that plasmin degradation of GpIb was due to a direct interaction between plasmin and GpIb and that this effect was mediated by the lysine binding region of the plasmin molecule
Reilly et al., Thromb Res 1993 : The goal of this study was to assess whether biologically active recombinant plasminogen activator inhibitor-1 ( rPAI-1 ), could antagonize the inhibitory effects of plasmin on GPIb