Gene interactions and pathways from curated databases and text-mining

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DYNLRB1 — TLR2

Text-mined interactions from Literome

Aliprantis et al., EMBO J 2000 : Here we show that the adaptor molecule, myeloid differentiation factor 88 ( MyD88 ), mediates both apoptosis and nuclear factor-kappaB (NF-kappaB) activation by BLP stimulated TLR2
Wang et al., J Biol Chem 2002 (MAP Kinase Signaling System) : However, BLP strongly enhanced TLR2 expression in non tolerized THP-1 cells, whereas LPS stimulation had no effect ... More importantly, pretreatment of THP-1 cells with BLP strongly inhibited TLR2 activation in response to subsequent BLP stimulation ... In contrast, LPS tolerance did not prevent BLP induced TLR2 overexpression
Matsumura et al., Immunology 2003 : The expression of TLR2 protein by hepatocytes was also remarkably up-regulated by IL-1alpha and, to a lesser extent, by TNF-alpha as well, but not by LPS or BLP