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IL1RN — PTGS2
Text-mined interactions from Literome
La et al., Mol Carcinog 2001
(Carcinoma, Squamous Cell...) :
In icIL-1Ra-JWF2 cells, however,
cyclooxygenase-2 mRNA levels were dramatically reduced and shown to be transcriptionally
regulated by
icIL-1Ra
Palmer et al., Arthritis Res Ther 2004
:
Indomethacin increased IL-1beta induced IL-1Ra secretion in synovial fibroblasts and de-differentiated chondrocytes, suggesting that inhibition of
COX-2 may indeed
enhance IL-1beta induced
IL-1Ra production
ViganĂ² et al., Am J Respir Crit Care Med 1997
:
COX-2 expression and PGE2 formation were
inhibited by dexamethasone ( 2 microM ), cycloheximide ( 10 microM ), and IL-1-receptor antagonist
(IL-1 ra) ( 250 ng/ml ), independently
Kniss et al., Am J Obstet Gynecol 1997
:
Experiments were conducted to examine whether
interleukin-1 receptor antagonist could
suppress interleukin-1 induced
cyclooxygenase-2 expression ... Northern and Western analyses revealed that
interleukin-1 receptor antagonist blocked interleukin-1 alpha induced expression of
cyclooxygenase-2 messenger ribonucleic acid transcripts and the subsequent appearance of cyclooxygenase-2 protein