◀ Back to IL15

IL15 — SOCS1

Text-mined interactions from Literome

Cornish et al., J Biol Chem 2003 : SOCS-1 expression is induced by interleukin (IL) 2, IL-4, IL-7, and IL-15 , and SOCS-1-deficient T cells show increased proliferation and prolonged survival in response to IL-2 and IL-4
Ilangumaran et al., Blood 2003 : Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes
Ilangumaran et al., J Immunol 2003 (Lymphoproliferative Disorders) : Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes
Chong et al., J Immunol 2004 (Diabetes Mellitus, Type 1...) : Additionally, IFN-gamma induced class I MHC up-regulation and TNF- and IFN-gamma induced IL-15 expression by beta cells were inhibited by SOCS-1 , which correlated with suppressed 8.3 T cell proliferation in vitro
Davey et al., Tissue Antigens 2006 : In addition, SOCS1 has a complex role in T cell activation, and studies have revealed significant roles for SOCS1 in the regulation of IL-4, IL-12 and IL-15 in vivo
Ramsborg et al., Exp Hematol 2007 (Inflammation) : IL-15 also induced expression of four suppressors of cytokine signaling (SOCS) family genes ( SOCS1-3 , cytokine-inducible SH2 containing protein ), which are classical negative regulators of cytokine signaling