Shtutman et al., Proc Natl Acad Sci U S A 1999
(Colonic Neoplasms) :
Inhibitors of beta-catenin activation, wild-type adenomatous polyposis coli, axin , and the cytoplasmic tail of cadherin suppressed cyclin D1 promoter activity in colon cancer cells
Hsu et al., J Cell Biol 2001
:
Axin attenuated the expression of cyclin D1 , a Wnt target that promotes the growth and differentiation of mammary lobulo-alveoli
Pradeep et al., Oncogene 2004
(Stomach Neoplasms) :
In addition, G-17 mediated increase in cyclin D1 transcription was significantly attenuated by axin or dominant negative ( dn ) T-cell factor 4 ( TCF4 ), suggesting crosstalk of G-17 with the Wnt signaling pathway