Gene interactions and pathways from curated databases and text-mining

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HLA-DRA — TGFB1

Text-mined interactions from Literome

Pazmany et al., J Neuroimmunol 2000 : Effect of transforming growth factor-beta1 on microglial MHC-class II expression
Delvig et al., J Leukoc Biol 2002 : Consistent with the functional data, TGF-beta1 reduced the constitutive expression of MHC class II transactivator ( CIITA ), MHC class II (MHC-II), invariant chain, and DO mRNA, whereas IFN-gamma up-regulated the expression of CIITA and MHC-II mRNA without affecting invariant chain or DO mRNA
Arai et al., Eur J Immunol 2003 : TGF-beta1-treatment slightly enhanced surface expression of sIgM, but not of MHC class II molecules
Johns et al., Brain Res 1992 (Astrocytoma) : Transforming growth factor-beta 1 differentially regulates proliferation and MHC class-II antigen expression in forebrain and brainstem astrocyte primary cultures ... The disparate responses of brainstem and forebrain astrocytes to transforming growth factor-beta 1 treatment were not limited to effects on cell growth, since transforming growth factor-beta 1 could block interferon-gamma induced MHC class-II antigen expression on cultured brainstem astrocytes but not on forebrain cells
Loughlin et al., Immunology 1993 : In contrast transforming growth factor-beta 1 ( TGF-beta 1 ) causes a reduction in expression of MHC class II on macrophages and of FcR on both cell types
Ljunggren et al., J Reprod Immunol 1998 : TNF-alpha and TGF-beta1 inhibited the IFN-gamma induced MHC class II expression