UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF1

CTNND1 — IGF1

Pathways - manually collected, often from reviews:

NCI Pathway Database Stabilization and expansion of the E-cadherin adherens junction: IGF1 (IGF1) → E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin complex (CDH1-CTNNB1-CTNNA1-CTNND1) (modification, collaborate)
Qian et al., EMBO J 2004
Evidence: assay, physical interaction

Text-mined interactions from Literome

Fagerström et al., J Biol Chem 1998 (Neuroblastoma) : The TPA induced p130cas phosphorylation increased within 5 min of stimulation and persisted for at least 4 days, whereas bFGF/IGF-I induced p130cas phosphorylation was biphasic
Fujita et al., J Biochem 1998 : These results indicate that the opposite regulation of Cas phosphorylation by insulin and IGF-I may be mediated through different properties of their receptors, and that the interaction of the insulin receptor with SHP-2 may play an important role in determining the tyrosine-phosphorylation state of Cas