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CCND2 — CDKN1B

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of CCND2-CDK4-CDKN1B → MYC (increases) Bouchard et al., EMBO J 1999
  Evidence: We nowshow that p27 is rapidly and transiently sequestered by cyclin D2-Cdk4 complexesupon activation of Myc and that cyclin D2 is a direct target gene of Myc.
• KEGG Cell cycle: CDKN1B/CDKN1C → Complex of CCND1-CCND2-CCND3-CDK4-CDK6 (protein-protein, inhibition)
  
• KEGG Measles: CCND1/CCND2/CCND3/CCNE1/CCNE2 → CDKN1B (protein-protein, inhibition)
• WikiPathways Cell Cycle: CDKN1B → CCND3/CCND2 (inhibition)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CCND2 — CDKN1B (direct interaction, two hybrid) Rual et al., Nature 2005
• IRef Hprd Interaction: CCND2 — CDKN1B (two hybrid) Rual et al., Nature 2005
• IRef Intact Interaction: Complex of 15 proteins (association, tandem affinity purification) Varjosalo et al., Cell reports 2013
• IRef Intact Interaction: Complex of 27 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013
• IRef Intact Interaction: CCND2 — CDKN1B (physical association, two hybrid pooling approach) Rual et al., Nature 2005
• IRef Ophid Interaction: CCND2 — CDKN1B (aggregation, interologs mapping) Brown et al., Bioinformatics 2005