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CASP1 — CASP12

Text-mined interactions from Literome

de Bilbao et al., Neuroscience 2000 (Facial Nerve Injuries) : Similar results were obtained in interleukin-1 beta converting enzyme-deficient and wild-type mice, indicating that the interleukin-1 beta converting enzyme may not be required for caspase 3 activation
Kilic et al., Cell Death Differ 2002 : Formation of noncanonical high molecular weight caspase-3 and -6 complexes and activation of caspase-12 during serum starvation induced apoptosis in AKR-2B mouse fibroblasts
Feng et al., Am J Physiol Gastrointest Liver Physiol 2002 (Necrosis) : Caspase-3 was activated in primary hepatocytes by STS treatment, but caspase-9 and -12 were not activated , and caspase-3 activation is not dependent on caspase-8
Morishima et al., J Biol Chem 2002 : Cytochrome c-independent activation of caspase-9 by caspase-12 ... These results suggest that caspase-12 can activate caspase-9 without involvement of cytochrome c
Chan et al., Neurobiol Dis 2002 (Alzheimer Disease) : Moreover, activation of caspase-12 , an endoplasmic reticulum ( ER ) -associated caspase , is greatly increased in cells expressing mutant PS1
Yang et al., Nephron. Experimental nephrology 2004 (Necrosis) : Here we evaluate three caspase inhibitors : B-D-FMK ( pan caspase inhibitor ), Z-DEVDFMK ( predominantly Caspase-3 inhibitor ) and Z-VAD-FMK ( predominantly Caspase-1 and -3 inhibitor ) to ameliorate apoptosis induced by cisplatin in rat proximal tubular ( RPT ) cells
Messerli et al., Neoplasia (New York, N.Y.) 2004 (Glioma) : The specificity of this probe for caspase-1 is supported by various lines of evidence : 1 ) activation by purified caspase-1, but not another caspase in vitro ; 2 ) activation of the probe by infection of cells with a herpes simplex virus amplicon vector ( HGC-ICE-lacZ ) expressing a catalytically active caspase-1-lacZ fusion protein; 3 ) inhibition of HGC-ICE-lacZ vector induced activation of the probe by coincubation with the caspase-1 inhibitor YVAD-cmk, but not with a caspase-3 inhibitor ; and 4 ) activation of the probe following standard methods of inducing apoptosis with staurosporine, ganciclovir, or ionizing radiation in culture
Aoyama et al., J Cereb Blood Flow Metab 2005 (Acidosis) : Acidosis also increased caspase-12 mRNA expression, caspase-12 protein expression, cleavage of caspase-12 to its active form, and activation of caspase-3
Obeng et al., J Biol Chem 2005 : We further demonstrate that ER stress induced apoptosis is a caspase dependent process that does not require the expression of caspase-12 or caspase-4 but can be inhibited by overexpression of Bcl-x ( L ) or a dominant negative caspase-9
Guo et al., Cell Death Differ 2006 : Caspase-1 activation of caspase-6 in human apoptotic neurons
Nakano et al., Cardiovasc Res 2006 : A non-selective caspase inhibitor, z-VAD.fmk ( 100 microM ), inhibited apoptosis and cleavage of caspase-12 stimulated by thapsigargin, while a calpain inhibitor, MDL 28170 ( 120 microM ), inhibited caspase-12 cleavage but not apoptosis
Cervia et al., Apoptosis 2006 (Pituitary Neoplasms) : In addition, we provide evidence that euplotin C treatment results in rapid activation of ryanodine receptors, depletion of Ca2+ stores in the endoplasmic reticulum ( ER ), the release of cytochrome c from the mitochondria, activation of caspase-12 , and activation of caspase-3 , leading to apoptosis
Kumar et al., Cardiovasc Res 2007 (Acidosis...) : Simulated ischemia had no significant effect on caspase-8 cleavage, but induced cleavage of caspase-3 and caspase-12 and led to a slight release of cytochrome C. Prevention of cytosolic acidosis ( anoxia at pH ( o ) 7.4 ) had no effect on cytochrome C release, but significantly reduced apoptosis, attenuated cytosolic Ca2+ overload, and prevented cleavage of caspase-12
Fábián et al., J Virol 2007 (Carcinoma...) : While caspase-8 and caspase-9 are not involved in MTH-68/H induced apoptosis, activation of caspase-3 and caspase-12 was detected in virus infected PC12 cells
Lin et al., Biochem Biophys Res Commun 2007 (Spinocerebellar Ataxias) : PKCgamma SCA14 mutant proteins were shown to cause aggregation which initially resulted in endoplasmic reticulum ( ER ) stress and cell apoptosis as demonstrated by phosphorylation of PERK on Thr981, activation of caspase-12 , increases in BiP/GRP78 protein levels, and consequent activation of caspase-3
Park et al., Biochem Pharmacol 2011 : Further analysis using selective caspase inhibitors revealed that caspase-12 activation was required for activation of caspase-9 and -3 to the sufficient level for subsequent activation of caspase-7 and -8
Fang et al., J Immunol 2011 (Disease Resistance...) : Caspase-1 activation was partially impaired in NLRP3 ( -/- ) macrophages, whereas knockdown and knockout of AIM2 resulted in a clear decrease in caspase-1 activation in response to S. pneumoniae
LaRock et al., Cell Host Microbe 2012 : Caspase-1 activation antagonizes Yersinia survival in vivo, and consequently YopM inhibition of caspase-1 is required for Yersinia pathogenesis
Wang et al., Cell 1998 (Shock, Septic) : Murine caspase-11 , an ICE interacting protease, is essential for the activation of ICE ... Furthermore, we found that pro-caspase-11 physically interacts with pro-ICE in cells, and the expression of casp-11 is essential for activation of ICE ... Our data suggest that caspase-11 is a component of ICE complex and is required for the activation of ICE