Gene interactions and pathways from curated databases and text-mining

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EGF — MSK10

Text-mined interactions from Literome

Gupta et al., J Biol Chem 2002 (MAP Kinase Signaling System) : ATF1 can be phosphorylated by mitogen- and stress activated protein kinase 1 ( MSK1 ), which is activated by EGF and ERK1/2 ... Kinase-dead MSK1 mutants blocked EGF induction of a transfected c-jun gene suggesting that MSK1 or a similar family member is required for induced c-jun expression
Duncan et al., J Biol Chem 2006 : Furthermore, MSK1/2 control EGF induced IkappaB alpha promoter H3-Ser10 phosphorylation in the absence of elevated transcription