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MAPK3 — MKNK1
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
MKNK1
→
MAPK3
(directlyIncreases, MAPK3 Activity, MKNK1 Activity)
Evidence: Mitogen-activated protein kinases such as ERK phosphorylate and activate MNK1, which in turn is able to phosphorylate eIF4E
-
OpenBEL Selventa BEL large corpus:
MKNK1
→
MAPK3
(directlyIncreases, MKNK1 Activity)
Evidence: Mitogen-activated protein kinases such as ERK phosphorylate and activate MNK1, which in turn is able to phosphorylate eIF4E
-
KEGG Insulin signaling pathway:
MAPK1/MAPK3
→
MKNK1/MKNK2
(protein-protein, activation)
-
KEGG MAPK signaling pathway:
MAPK1/MAPK3
→
MKNK1/MKNK2
(protein-protein, phosphorylation)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ramesh et al., American journal of physiology. Renal physiology 2007
:
Inhibition of p38
MAPK and, to a lesser extent, ERK,
reduced cisplatin+endotoxin stimulated TNF-alpha production and phosphorylation of
Mnk1 and eIF4E
Das et al., J Cell Physiol 2013
(MAP Kinase Signaling System) :
Both PI 3 kinase and
Erk1/2 promoted phosphorylation of
Mnk-1 in response to TGFß