Gene interactions and pathways from curated databases and text-mining

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JUN — VEGFC

Pathways - manually collected, often from reviews:

  • KEGG Pathways in cancer: JUN → FIGF/PGF/VEGFA/VEGFB/VEGFC (gene expression, expression)

Text-mined interactions from Literome

Chien et al., Carcinogenesis 2009 (MAP Kinase Signaling System...) : VEGF-C induced JNK dependent nuclear translocation of c-Jun ... Furthermore, chromatin immunoprecipitation and reporter assays revealed that VEGF-C enhanced c-Jun binding to the cyclic adenosine 3',5'-monophosphate-response element of the COX-2 promoter and induced COX-2 expression
Wang et al., Blood 1997 : Furthermore, the c-Jun NH2-terminal kinase (JNK) , involved in growth activation and shown to mediate RAFTK signaling in other cell types, was activated by VRP stimulation