Gene interactions and pathways from curated databases and text-mining

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CAPN6 — PAFAH1B1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: CAPN6 — PAFAH1B1 (interaction, mapped from mint)
  • STRING interaction: PAFAH1B1 — CAPN6 (interaction, mapped from reactome)

Text-mined interactions from Literome

Yamada et al., Nat Med 2009 (Disease Models, Animal...) : Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly
Yamada et al., Int J Biochem Cell Biol 2010 (Genetic Diseases, Inborn...) : We further demonstrated that inhibition of calpain mediated LIS1 degradation increased LIS1 level at the cortex of the cell, resulting in therapeutic benefit using genetic mouse models with reduced levels of LIS1