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CR2 — IL6
Text-mined interactions from Literome
D'Addario et al., J Mol Biol 2001
:
To our knowledge this is the first report showing that the binding of a herpesvirus envelope glycoprotein to
CR2 on human B cells
results in the activation of the NF-kappaB transcription factor leading to the upregulation of
IL-6 gene expression in these lymphocytes
Klimas et al., Am J Med Sci 1992
(Autoimmune Diseases...) :
Analysis of the pleural effusion revealed an increased CD4/CD8 ratio because of an increased percentage of CD4+CD29+ helper memory T cells, lack of expression of the resting B-cell marker
CD21 , immune complex deposition and complement consumption,
increased relative levels of ANA, abnormally high levels of
IL-6 and soluble IL-2R, and detectable levels of IL-1b, IFN-g and TNF-a
Gagro et al., Eur J Immunol 1994
(Asthma) :
In this study we investigated the
effect of the Dermatophagoides pteronyssinus (Dpt) allergen and recombinant
interleukin ( rIL ) -4 on the expression of
CD21 and CD23 on T and B cells of asthmatic patients allergic to Dpt and of healthy controls
Frémeaux-Bacchi et al., Eur J Immunol 1998
:
Soluble
CD21 induced an increase in intracellular cGMP levels and the production of
IL-6 and TNF-alpha in IL-4 pretreated monocytes induced to express CD23 but not in unstimulated CD23- monocytes