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PTGS1 — TNF

Text-mined interactions from Literome

Yucel-Lindberg et al., J Dent Res 1999 : Neither IL-1beta, TNFalpha , nor the combination of these two cytokines affected COX-1 mRNA levels
Subbarayan et al., Cancer Res 2001 (Prostatic Neoplasms) : Because COX-2 levels were low in prostate smooth muscle cells, prostate stromal cells, and tumor cells, we also examined whether COX-1 and COX-2 gene expression was elevated in response to tumor necrosis factor-alpha (TNF-alpha) , a strong inducer of COX-2 expression
Yamada et al., Clin Exp Immunol 2002 (Urinary Bladder Neoplasms) : NS398, a specific COX-2 inhibitor, and indomethacin ( IM ), a COX-1 and COX-2 inhibitor, enhanced viable BCG induced cytotoxic activity and IFN-gamma and TNF-alpha production of PEC
Jiang et al., Mol Cell Biochem 2003 : In this study, the effect of phorbol 12-myristate 13-acetate ( PMA ), tumor necrosis factor alpha (TNFalpha), lipopolysaccharide (LPS) and macrophage-colony stimulating factor ( M-CSF ) on AA release and prostaglandin E2 ( PGE2 ) production and the expression of cPLA2 and COX-1 and -2 were investigated in U937 human pre-monocytic cells and fully differentiated macrophages
Tsai et al., Int Immunopharmacol 2004 : Interleukin (IL)-1beta ( 25 ng/ml ), IL-8 ( 25 ng/ml ), growth related oncogene-alpha ( GRO, 50 ng/ml ) and tumor necrosis factor-alpha ( TNF-alpha, 25 ng/ml ) stimulated the COX-1 protein production as demonstrated by Western blot and enhanced PGE2 synthesis in GMC, beginning on 2 h of incubation, and steadily enhanced TXB2 synthesis over a 24-h period
Diaz et al., Exp Cell Res 1998 : Analysis of fibroblast proteins showed the induction of cyclooxygenase-1 (Cox-1) by TGF-beta 1 and the induction of Cox-2 by IL-1 beta and TNF-alpha