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FGF1 — HSP90AA1

Text-mined interactions from Literome

Wesche et al., J Biol Chem 2006 (MAP Kinase Signaling System) : FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus ... We therefore investigated the requirement for Hsp90 in FGF translocation ... The data indicate that the drugs block translocation from endosomes to the cytosol implying that Hsp90 is required for translocation of FGF-1 and FGF-2 across the endosomal membrane
Ren et al., Mol Cancer Res 2006 : The results also show that inhibition of HSP90 with geldanamycin or 17- ( allylamino ) -17-demethoxygeldanamycin attenuates FGF1 induced binding of MUC1 to HSP90 and targeting of MUC1 to the mitochondrial outer membrane