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GATA2 — IL3

Text-mined interactions from Literome

Towatari et al., J Biol Chem 1995 : Regulation of GATA-2 phosphorylation by mitogen activated protein kinase and interleukin-3 ... Stimulation of progenitors with interleukin-3 (IL-3) results in enhanced phosphorylation of GATA-2 which occurs within 5 min. IL-3 is known to signal in part through mitogen activated protein ( MAP ) kinase, and evidence for MAP kinase signaling in the control of GATA-2 phosphorylation was obtained by genetically manipulating the MAP kinase pathway in COS cells using either constitutively activating or interfering mutants of MAP kinase kinase ... Furthermore, using an interfering mutant of MAP kinase kinase, we directly demonstrated a critical role for the MAP kinase pathway in the IL-3 dependent phosphorylation of GATA-2 in hematopoietic progenitor cells
Harigae et al., Genes Cells 1998 : In contrast, GATA-1 protein was expressed in PMCs and BMMCs after culture in the presence of IL3 and SCF