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CD40 — IRF1

Text-mined interactions from Literome

Wagner et al., Blood 2002 : Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1
Moschonas et al., Mol Cell Biol 2008 (Neoplasms) : We show that unlike interferon signaling, which triggers the STAT1 mediated transcriptional activation of IRF-1, the ligation of CD40 in carcinomas induces the rapid upregulation of IRF-1 in a STAT1 independent but NF-kappaB dependent manner
Drew et al., J Interferon Cytokine Res 1995 : We demonstrated here that TNF-alpha induced binding of NF kappa B p50 and p65 to the NF kappa B-like element of the MHC class I promoter termed region I and IFN-gamma induced binding of IRF-1 to the adjacent interferon consensus sequence ( ICS )
Gupta et al., J Immunol 1998 : IFN regulatory factor 1 (IRF-1) is a transcription factor activated by either CD40 or cytokines ... In contrast to induction of STATs by cytokines, the IRF-1 GAS binding complex activated by CD40 , TNF-alpha, or EBV contains Rel proteins, specifically p50 and p65