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CXCL12 — TP53

Text-mined interactions from Literome

Moskovits et al., Cancer Res 2006 (Neoplasm Invasiveness...) : We now report that p53 can suppress the production of the chemokine SDF-1 in cultured fibroblasts of both human and mouse origin
Kojima et al., Blood 2011 (Leukemia, Myeloid, Acute) : p53 activation by Nutlin-3a was not cytotoxic to stromal cells, but reduced CXCL12 mRNA levels and secretion of CXCL12 partially through p53 mediated HIF-1a down-regulation
Panka et al., Molecular cancer 2013 (Carcinoma, Renal Cell) : Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction , and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells