Gene interactions and pathways from curated databases and text-mining

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FCGR1A — STAT1

Text-mined interactions from Literome

Coccia et al., Int Immunol 1999 : Taken together these results indicate that STAT1 plays a pivotal role in the differentiation/maturation process of monocytes as an early transcription factor initially activated by adherence and then able to modulate the expression of functional genes, such as ICAM-1 and FcgammaRI
Aittomäki et al., Blood 2002 : The basal activity of the natural FcgammaRI promoter was strictly dependent on PU.1, and IFN-gamma induction required both PU.1 and Stat1 ... In contrast, Stat1 did not interact with basal transcription machinery, but the Stat1 mediated activation of FcgammaRI promoter critically required CREB binding protein (CBP)/p300
Kårehed et al., Mol Immunol 2007 : Our results suggest that IFN-gamma induced increase of FcgammaRI expression requires the integration of two signalling events : PKR dependent Stat1 serine 727 phosphorylation, and activation of NFkappaB
Feldman et al., J Immunol 1995 : IgG immune complexes inhibit IFN-gamma induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 ( Stat1 ) transcription factor
Bovolenta et al., FEBS Lett 1996 : This is the first demonstration that in human neutrophils, the induction by G-CSF of Fc(gammaRI) gene expression may be mediated by the binding of STAT1 and STAT3 to the GRR sequence