Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Li et al., Neurobiol Aging 2012 (Alzheimer Disease...) : In SK-NS-H cells, upregulation of AGEs receptor ( RAGE ), inhibition of Akt, and activation of glycogen synthase kinase-3 ( GSK-3 ) , Erk1/2, and p38 were observed after treatment with AGEs
Li et al., Cell death & disease 2013 : We observed that glycation exacerbated neurotoxicity of Aß with upregulation of receptor for AGE (RAGE) and activation of glycogen synthase kinase-3 ( GSK-3 ) , whereas simultaneous application of RAGE antibody or GSK-3 inhibitor reversed the neuronal damages aggravated by glycated Aß