Gene interactions and pathways from curated databases and text-mining

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CD4 — TBCA

Text-mined interactions from Literome

Kochetkova et al., J Immunol 2011 (Arthritis, Experimental) : To identify the responsible regulatory CD4 ( + ) T cells making the host refractory to CIA, Salmonella-CFA/I induced CD39 ( + ) CD4 ( + ) T cells with enhanced apyrase activity relative to Salmonella vector immunized mice ... Although each adoptively transferred Salmonella-CFA/I induced Foxp3 ( - ) and Foxp3 ( + ) CD39 ( + ) CD4 ( + ) T cells could protect against CIA, each subset was not as efficacious as total CD39 ( + ) CD4 ( + ) T cells, suggesting their interdependence for optimal protection
Murphy et al., Infect Immun 1998 (Cryptococcosis) : CneF-CFA induces CD4+ T cells responsible for delayed-type hypersensitivity ( DTH ) reactivity and for amplification of the anticryptococcal DTH response, whereas HKC induce CD4+ and CD8+ T cells involved in anticryptococcal DTH reactivity and activated T cells which directly kill C. neoformans cells