Gene interactions and pathways from curated databases and text-mining

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MMP9 — TNFSF12

Text-mined interactions from Literome

Kim et al., Circ J 2004 (Carotid Stenosis) : TWEAK induced activation of MMP-9 was mediated by activation of NF-kappaB
Polavarapu et al., J Neurosci 2005 : TWEAK did not increase MMP-9 activity or BBB permeability when injected into mice genetically deficient in the NF-kappaB family member p50
Kumar et al., J Immunol 2009 (Inflammation) : TWEAK induced expression of proinflammatory genes such as MMP-9 , CCL-2, and VCAM-1 was also reduced in TAK1 ( -/- ) MEF compared with wild-type MEF ... Furthermore, the activation of NF-kappaB and the expression of MMP-9 in response to TWEAK involved the upstream activation of Akt kinase
Stephan et al., Journal of neuroinflammation 2013 : Moreover, it has been shown by others that, when injected into mice brains, TWEAK disrupts the architecture of the BBB and induces expression of matrix metalloproteinase-9 (MMP-9) in the brain
Pettersen et al., Int J Oncol 2013 (Cell Transformation, Neoplastic...) : Moreover, TWEAK induces the release of matrix metalloprotease-9 (MMP-9) in neuroblastoma cells, suggesting that TWEAK may play a role in the invasive phase of neuroblastoma tumorigenesis