Gene interactions and pathways from curated databases and text-mining

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SLC2A1 — SLC5A1

Text-mined interactions from Literome

Helliwell et al., Biochem J 2000 (Diabetes Mellitus, Experimental) : In general, GLUT2 levels increased up to 4-fold within minutes and with only minimal changes in GLUT5 or SGLT1 levels, demonstrating that GLUT2 trafficks by a rapid trafficking pathway distinct from that of GLUT5 and SGLT1
Vestri et al., J Membr Biol 2001 (Diabetes Mellitus, Experimental) : Compared to NS rats, HS rats increased ( P < 0.05 ) SGLT2, GLUT2 , and GLUT1 expression by approximately 100 %, with no change in SGLT1 mRNA expression, and LS rats increased ( P < 0.05 ) GLUT1 gene expression by approximately 150 %, with no changes in other transporters
Scow et al., J Surg Res 2011 : Transporter mediated glucose uptake was studied in rat jejunum using everted sleeves under seven conditions : Control, SGLT1 inhibition ( phlorizin ), GLUT2 inhibition ( phloretin ), both SGLT1 and GLUT2 inhibition , PKC inhibition ( calphostin C or chelerythrine ), and disruption of cellular cytostructure ( nocodazole )