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LANCL1 — TNF
Text-mined interactions from Literome
Jana et al., J Neurochem 2003
:
The present study was undertaken to explore the
role of interleukin-12 (IL-12)
p40 in the expression of
TNF-alpha in microglia ... In addition to BV-2 microglial cells, p70, p402 and
p40 also
induced the production of
TNF-alpha in mouse primary microglia and peritoneal macrophages
Berthier-Vergnes et al., FEBS Lett 2005
(Hypersensitivity) :
TNF-alpha enhances phenotypic and functional maturation of human epidermal Langerhans cells and
induces IL-12
p40 and IP-10/CXCL-10 production ... More importantly,
TNF-alpha induced LC to produce both IFN-gamma-inducible-protein IP-10/CXCL10, a Th1 attracting chemokine and IL-12
p40
Roggen et al., Toxicol Lett 2006
(Hypersensitivity) :
PGE ( 2 ) is synergistic with IL-1beta and
TNF-alpha in the induction of functional and phenotypic maturation of DC and
induce IL12
p40 production
Ryan et al., Vet Immunol Immunopathol 2010
(Actinomycetales Infections...) :
On day 12,
TNF-a induction in monocyte derived macrophages and IL-12
p40 induction in BAL macrophages infected with R. equi was significantly higher in foals treated with PPVO than in controls
Kramp et al., Clin Exp Immunol 2011
(Tuberculosis) :
TNF-a treatment
induced a decrease in TNF-a,
IL-12p40 and IL-10 mRNA levels in peritoneal cells following PPD stimulation while live M. tuberculosis caused an increase in TNF-a mRNA and a decrease in the IL-10 mRNA expression