Gene interactions and pathways from curated databases and text-mining

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FCGR1A — TNF

Text-mined interactions from Literome

van Roon et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid) : Consistent with these effects on SF macrophages, CD64-RiA also inhibited TNFalpha production, interleukin-1beta production, and cartilage degrading activity of RA synovial tissue explants
Debets et al., J Immunol 1990 : Cross linking of both Fc gamma RI and Fc gamma RII induces secretion of tumor necrosis factor by human monocytes, requiring high affinity Fc-Fc gamma R interactions
Miller-Graziano et al., J Trauma 1990 (Burns...) : IgG stimulation of patients ' MO through FcRI not only stimulated TNF alpha , IL-6, and PGE2 levels, but also greatly augmented the levels of these monokines produced after subsequent bacterial challenge
Hilda et al., FEMS Immunol Med Microbiol 2012 : Increased expression of CD32, CD64 , TLR4, and CXCR3 ; increased TNF-a secretion ; and downregulation of early apoptosis were observed in H37Rv infected neutrophils
Gessl et al., Scand J Immunol 1994 : TNF-alpha , as well as interferon-gamma (IFN-gamma) or interleukin-6 (IL-6) had a significant up-regulating effect on U937 expression of Fc gamma RI/CD64 ... In contrast to U937 cells, TNF-alpha did not enhance significantly Fc gamma RI expression on human monocytes
Knowles et al., Am J Physiol 1997 (Anoxia) : During reoxygenation, both whole blood PMN phagocytosis and bactericidal activity were reduced in the presence of IL-8, TNF-alpha , or IL-1beta, and in subsets of PMN with reduced phagocytosis H/R reduced CD64 , CD32w, CD16, CD35, and CD11b/CD18 expression in the presence of each cytokine