Gene interactions and pathways from curated databases and text-mining

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IL23A — TNF

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Shan et al., Cell Mol Immunol 2006 (Carcinoma...) : IL-23 also promoted the production of Th1 cytokines such as IFN-gamma, IL-12 and TNF-alpha
Hao et al., Cancer Immunol Immunother 2006 (Neoplasms) : IL-23 can enhance the proliferation of memory T cells and the production of IFN-gamma, IL-12 and TNF-alpha from activated T cells
Husted et al., Inflamm Res 2006 (Reperfusion Injury) : Finally, isolated Kupffer cells produced TNFalpha in response to IL-23 , but not IL-12, suggesting that IL-23 may be the relevant initiator of the hepatic inflammatory response to ischemia/reperfusion
Liu et al., Rheumatology (Oxford) 2007 (Arthritis, Rheumatoid) : To explore the source of the p19 subunit of interleukin-23 (IL-23) in joints with rheumatoid arthritis ( RA ), the effects of IL-1beta and tumour necrosis factor (TNF)-alpha on IL-23 gene expression in RA fibroblast-like synoviocytes and the effect of IL-23 on proinflammatory cytokines
Kageyama et al., Rheumatol Int 2007 (Arthritis, Gouty...) : TNF-alpha induced MIP-3alpha but not IL-23 production in cultured synovial cells from RA patients
Fukuda et al., Int J Oncol 2010 (Carcinoma, Squamous Cell...) : IL-23 , which constitutively expressed in oral cancer, was enhanced by TNF-alpha and IL-23
Fukuda et al., Mol Med Report 2010 : IL-23 and its receptor mRNAs and proteins were spontaneously expressed, and IL-23 was increased by TNF-a stimulation in the oral cancer cells