Gene interactions and pathways from curated databases and text-mining

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IGF1 — NGF

Text-mined interactions from Literome

Jamen et al., J Neurochem 2002 (MAP Kinase Signaling System) : NGF and IGF-1 increased endogenous PAC1 mRNA levels, and the NGF induced up-regulation is the result of an increase in transcription from PAC1 promoter instead of an increase in mRNA stability
Zhang et al., Regul Pept 2012 (Cystitis) : Regulation of IGF-1 but not TGF-ß1 by NGF in the smooth muscle of the inflamed urinary bladder ... The effect of NGF on regulating IGF-1 expression was further confirmed in bladder smooth muscle culture showing that exogenous NGF increased the mRNA level of IGF-1 after 30 min to 1 h stimulation
Burgess et al., J Biol Chem 1987 : 7 S nerve growth factor , but not beta-nerve growth factor, also inhibited 125I-IGF-I binding
Fernyhough et al., Brain Res 1993 : Specific anti-NGF antiserum inhibited the regenerative response to NGF but failed to block the response to IGF-I, supporting the view that IGF-I was acting directly on sensory neurones rather than stimulating NGF production by non-neuronal cells