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KHSRP — TNF
Text-mined interactions from Literome
Rekdal et al., Mediators Inflamm 1994
:
The present study was performed to examine whether residues 36-62 of TNFalpha contain the chemotactic domain of TNFalpha, and whether the p55 and
p75 TNF receptors are
involved in
TNFalpha induced chemotaxis
Beyaert et al., J Biol Chem 1995
:
Taken together, our data demonstrate that the p75 TNF receptor is phosphorylated and associated with CK-1, which negatively regulates
p75 mediated
TNF signaling
Amrani et al., Am J Respir Cell Mol Biol 1996
:
Interestingly, activation of the TNF alpha-p75 receptor with a selective agonist, recombinant TNF
alpha-p75 ( rTNF alpha-p75 ), or
inhibition of the
TNF alpha-p75 receptor with utr-1, an inhibitory anti-TNF alpha-p75 receptor antibody, had no effect on TNF alpha augmented calcium transients or on myocyte growth
Peschon et al., J Immunol 1998
(Acute-Phase Reaction...) :
We have examined the
roles of p55 and
p75 in mediating and modulating the activity of
TNF in vivo by generating and examining mice genetically deficient in these receptors ... In summary, these data help clarify the biologic
roles of p55 and
p75 in mediating and modulating the biologic activity of
TNF and provide genetic evidence for an antagonistic role of p75 in vivo