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RBBP7 — SIRT1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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Gene Ontology Complexes ESC/E(Z) complex:
ESC/E(Z) complex complex (SIRT1-HDAC2-JARID2-MTF2-RBBP7-PHF19-EZH2-H2AFY2-AEBP2-PHF1)
Pasini et al., EMBO J 2004, Kuzmichev et al., Proc Natl Acad Sci U S A 2005, Buschbeck et al., Nature structural & molecular biology 2009, Pasini et al., Nature 2010, Ballaré et al., Nature structural & molecular biology 2012, Cai et al., Mol Cell 2013, Chu et al., Proc Natl Acad Sci U S A 2014
Text-mined interactions from Literome
Ferland et al., Neuroscience 2011
:
In addition, since histone deacetylases ( HDACs ) contribute to the acetylation state of histones, we investigated the effects of two
HDAC inhibitors, sodium butyrate, a class I and II global HDAC inhibitor, and sirtinol, a class III
sirtuin inhibitor , on acetylation of histone 3 (H3) and H4
Alamdari et al., Metabolism 2013
(Muscular Atrophy) :
In recent studies, inhibition of p300/HAT expression and activity and stimulation of
SIRT1 dependent
HDAC activity reduced glucocorticoid induced catabolic response in skeletal muscle, providing further evidence that hyperacetylation plays a role in muscle wasting