Gene interactions and pathways from curated databases and text-mining

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MMP12 — MMP3

Text-mined interactions from Literome

Tan et al., Am J Respir Cell Mol Biol 2006 (Pneumonia...) : No increases in RNA levels of MMP-2, MMP-9 , or MMP-8 were found, but levels of MMP-7, MMP-12 , and MMP-13 RNA did increase at 14 d
Choi et al., J Neurochem 2008 (Nerve Degeneration...) : Under the cell stress condition, MMP-3 is released as actMMP-3 rather than the proform ( proMMP-3 ), and catalytically active MMP-3 added to the medium does not cause cell death
Madala et al., J Immunol 2010 (Fibrosis...) : Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like MMP12 , MMP13 expression was highly dependent on IL-13 and type II-IL-4 receptor signaling
Li et al., PloS one 2012 (Disease Models, Animal...) : Similar results were observed in the study using MMP408 , a pharmacological inhibitor of MMP-12
Coker et al., Am J Physiol 1998 (Heart Failure) : With pacing CHF, the relative abundance for MMP-1 increased to 319 +/- 94 %, MMP-2 increased to 194 +/- 31 %, and MMP-3 increased to 493 +/- 159 % ( all P < 0.05 )