◀ Back to MAPK10

MAPK10 — MITF

Text-mined interactions from Literome

Ahn et al., Arch Dermatol Res 2008 (MAP Kinase Signaling System) : Furthermore, p38 MAPK functionally regulated the LPS induced melanin formation in melanocytes ; a p38 MAPK inhibitor, SB203580, almost completely attenuated the LPS mediated up-regulation of melanin synthesis and induction of MITF and tyrosinase expression
Jiang et al., Life Sci 2009 (Melanoma, Experimental) : Furthermore, Western blot analysis revealed that THSG elevated the level of phosphorylation of p38 mitogen activated protein kinase ( p38 MAPK ) significantly at 1-6 h ; a p38 MAPK inhibitor, SB203580, almost completely attenuated the THSG mediated up-regulation of melanin synthesis and induction of MITF and tyrosinase expression
Park et al., International journal of cell biology 2009 : Then the activated MAPK/ERK caused an acute phosphorylation of MITF , followed by proteosome mediated degradation of MITF, the key transcription factor for melanogenic proteins [ Wu et al. ( 2000 ) Gene & Development : 14 ]
Wu et al., J Biomed Sci 2011 (Hyperpigmentation...) : Cpc exerted dual antimelanogenic mechanisms by upregulation of MAPK/ERK dependent degradation of MITF and downregulation of p38 MAPK regulated CREB activation to modulate melanin formation
Zhou et al., J Ethnopharmacol 2012 (Melanoma, Experimental) : The special p38 MAPK inhibitor, SB203580, and protein kinase A (PKA) inhibitor, H89, both attenuated the AVE induced up-regulation of MITF and tyrosinase expression in B16F10 cells and NHMC ... AVE exerts its improving effect on melanogenesis mainly by p38 MAPK activation and MITF induction of tyrosinase