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CA2 — STIM1
Text-mined interactions from Literome
Bleich et al., Pflugers Arch 1999
:
As before,
STIM enhanced
[Ca2+ ] i
Naghdi et al., J Cell Sci 2010
:
Mitochondrial Ca2+ uptake and not mitochondrial motility is required for
STIM1-Orai1 dependent store operated
Ca2+ entry
Berry et al., Prostate 2011
(Calcium Signaling) :
Reduced
STIM1 expression in prostate stromal cells
led to a reduction in basal
Ca2+ levels, the amount of Ca2+ released by thapsigargin and a reduction in store filling following TG-induced store depletion
Hulot et al., Circulation 2011
(Calcium Signaling...) :
A potential route is store operated Ca2+ entry, a drug-inducible mechanism for
Ca2+ signaling that
requires stromal interaction molecule 1 (STIM1)
Pham et al., Cell Calcium 2012
:
Our results suggest that
Stim1 oligomerization and puncta formation may be additionally
regulated either by local
Ca2+ levels near the ER membrane or by as yet unidentified Ca2+ dependent proteins interacting with the cytoplasmic domains of Stim1
Dickson et al., Proc Natl Acad Sci U S A 2012
(Calcium Signaling) :
Orai-STIM mediated
Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe
Lee et al., Biochem J 2013
:
STIM1 negatively
regulates Ca2+ release from the sarcoplasmic reticulum in skeletal myotubes ... These results suggest that
STIM1 negatively
regulates Ca2+ release from the SR through the direct interaction of the STIM1 C-terminus with DHPR, and that STIM1 is involved in both ECC and SOCE in skeletal muscle
Zhang et al., Mol Cell Biol 2013
(Calcium Signaling) :
Mechanisms of
STIM1 Activation of Store Independent Leukotriene C4-Regulated
Ca2+ Channels