Gene interactions and pathways from curated databases and text-mining

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IFI44 — IL1A

Text-mined interactions from Literome

Matthews et al., Cytokine 1999 (Thymoma...) : Interleukin 1 (IL-1) activates p42/p44 and p38 mitogen activated protein kinases ( MAP kinases ) in target cells
Miwa et al., Endocrinology 1999 : IL-1alpha time-dependently stimulated the phosphorylation of both p42/p44 mitogen activated protein ( MAP ) kinase and p38 MAP kinase
Vela et al., Mol Cell Neurosci 2002 : Regarding intracellular signaling, IL-1beta activated the p38 mitogen activated protein kinase ( MAPK ) but not the p42/p44 MAPK and, when combined with growth factors, intensified p38 activation but inhibited the growth-factor induced p42/p44 activation
Lee et al., World J Gastroenterol 2006 (MAP Kinase Signaling System) : Based on these results, IL-1beta induced p44/42 MAP kinase activation is mediated by the Gi protein, tyrosine kinase, phospholipase C (PLC) and PKC
Eda et al., Rheumatol Int 2011 (MAP Kinase Signaling System) : IL-1ß and TNF-a activated the intracellular mitogen activated protein kinases ( MAPKs ) : p44/42 MAPK, p38, and c-Jun N-terminal kinase (JNK) as well as nuclear factor-?B ( NF-?B ) in osteoblasts