Gene interactions and pathways from curated databases and text-mining

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ARF6 — CTBP2

Text-mined interactions from Literome

Paliwal et al., Mol Cell Biol 2006 (Colonic Neoplasms) : Interaction with ARF resulted in proteasome dependent CtBP degradation ... Both ARF induced CtBP degradation and CtBP small interfering RNA led to p53 independent apoptosis in colon cancer cells ... ARF induction of apoptosis was dependent on its ability to interact with CtBP , and reversal of ARF induced CtBP depletion by CtBP overexpression abrogated ARF induced apoptosis
Paliwal et al., Cancer Res 2007 (Lung Neoplasms) : Furthermore, overexpression of CtBP2 in ARF expressing cells enhanced cell migration, and an ARF mutant defective in CtBP-family binding was impaired in its ability to inhibit cell migration induced by CtBP2