Gene interactions and pathways from curated databases and text-mining

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ARF6 — ZBTB7A

Text-mined interactions from Literome

Maeda et al., Nature 2005 (Cell Transformation, Neoplastic...) : Pokemon can specifically repress the transcription of the tumour suppressor gene ARF through direct binding
Choi et al., J Biol Chem 2009 (Bone Neoplasms...) : Our investigations on transcriptional repression of the p53 pathway revealed that FBI-1 represses transcription of ARF , Hdm2 ( human analogue of mouse double minute oncogene ), and p21CIP1 ( hereafter indicated as p21 ) but not of p53
Zhao et al., Asian Pac J Trop Med 2011 (Carcinoma, Hepatocellular...) : The proto-oncogene Pokemon can inhibit P14ARF by specific transcription regulation of cell cycle and can induce tumors