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AVP — TGFB1
Text-mined interactions from Literome
Higashiyama et al., Hypertens Res 1999
:
TGF-beta1 did not
affect [ 3H ]
AVP receptor binding
Yan-Hong et al., J Cardiovasc Pharmacol 2010
:
AVP induced
transforming growth factor-beta1 ( TGF-beta1 ) secretion was detected by enzyme linked immunosorbent assay ... Meanwhile, AVP significantly increased
TGF-beta1 secretion of CFs in a dose dependent manner, and this effect was also
blocked by 10 mol/L [ d ( CH2 ) 5Tyr ( Me ) ]
AVP ... However, the maximum production of biologic active
TGF-beta1 induced by
AVP is far less than the dose of exogenous TGF-beta1 needed to induce CFs-myofibroblast transformation ... AVP can induce CFs-myofibroblast transformation via its V1a receptor,
AVP induced increase of
TGF-beta1 synthesis, which also is mediated by V1a receptor, may play a minor role in the transformation
Raber et al., Neurochem Int 1997
:
Taken with a previous report that
TGF-beta 1 specifically
inhibits AVP release by acetylcholine, these results suggest that TGF-beta 1 may modulate HPA axis activation, by antagonizing ( acetylcholine evoked ) CRF and AVP release