Gene interactions and pathways from curated databases and text-mining

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ITGA2 — TGFB1

Text-mined interactions from Literome

Bellis et al., J Cell Physiol 1999 : HD3 colon epithelial cells maintain elevated levels of integrin alpha2beta1 heterodimers, strong binding to collagen I, and autocrine regulation by TGFbeta1 , which converts beta1 integrin into the mature cell surface form
Zhou et al., Oral Dis 2009 (Fibromatosis, Gingival) : The increased expression of integrin alpha2 and the increased response to TGF-beta1 of HGF fibroblasts may be related to the excessive collagen deposition in HGF patients
Kodama et al., Endocr J 1997 : We have demonstrated that osteoblastic differentiation and down-regulation of transforming growth factor ( TGF ) -beta receptors requires the interaction of type I collagen with alpha 2 beta 1 integrin ( J Biol Chem 271 : 3938-3944, 1996 )
Takeuchi et al., J Biol Chem 1997 : Interaction of type I collagen ( COL ( I ) ) with alpha2beta1 integrin causes differentiation and transforming growth factor ( TGF ) -beta receptor down-regulation in osteoblastic cells ( Takeuchi, Y., Nakayama, K., and Matsumoto, T. ( 1996 ) J. Biol. Chem. 271, 3938-3644 )