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TGFB1 — TNFRSF11B

Text-mined interactions from Literome

Sakata et al., J Bone Miner Res 1999 : However, IL-6 and transforming growth factor-beta had little effect on OPG/OCIF mRNA levels in HPDL
Chagraoui et al., Exp Hematol 2003 : Within the bone microenvironment, OPG is abundantly produced by osteoblast/stromal cells, and its expression is regulated by transforming growth factor-beta(1) ( TGF-beta(1) )
Martin et al., Bone 2004 (Bone Resorption) : Growth factors released from the matrix during Phase I were assumed to cause two negative feedback effects : ( 1 ) the inhibitory effect of transforming growth factor-beta1 ( TGFbeta1 ) -induced production of OPG by marrow osteoblast stromal cells, reducing effective RANKL ; ( 2 ) the apoptosis of osteoclast nuclei assumed to occur at high concentrations of TGFbeta
Wang et al., Exp Hematol 2004 (Myeloproliferative Disorders...) : These results suggest that osteosclerosis in IMF may be related to overproduction of OPG and enhanced level of OPG is not due to the effect of TGF-beta1 on the BMS cells
Hase et al., Arthritis Rheum 2008 (Arthritis, Rheumatoid...) : Coculture of osteoclast precursors with rheumatoid synovial fibroblasts induces osteoclastogenesis via transforming growth factor beta mediated down-regulation of osteoprotegerin
Schwartz et al., Biomaterials 2009 : Exogenous TGF-beta1 increased OPG production in a dose dependent manner on all surfaces, and this was prevented by adding blocking antibody to the TGF-beta type II receptor or by reducing TGF-beta1 binding to the receptor by adding exogenous soluble type II receptor ... These results indicate that substrate dependent OPG production is regulated by TGF-beta1 , PKC, and alpha2beta1 and suggest a mechanism by which alpha2beta1 signaling increases PKC, resulting in TGF-beta1 production and TGF-beta1 then acts on its receptor to increase transcription of OPG
Katopodis et al., Anticancer Res 2009 (Bone Neoplasms...) : The enhancement of the OPG expression in PC-3 cells by MG-63 cells is not mediated by IGF-1, IL-6 and TGFbeta1
Takai et al., J Biol Chem 1998 : Western blot analysis and an enzyme linked immunosorbent assay revealed that TGF-beta1 significantly increased the secretion of OPG/OCIF protein by ST2 cells at 6-24 h
Murakami et al., Biochem Biophys Res Commun 1998 : Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells