◀ Back to IL4
IL4 — TIMP2
Text-mined interactions from Literome
Ihn et al., J Immunol 2002
(MAP Kinase Signaling System) :
IL-4 induction of
TIMP-2 expression was dependent upon transcription ... The p38 mitogen activated protein kinase ( MAPK ) inhibitors SB202190 and SB203580 suppressed
IL-4 induced
TIMP-2 expression, suggesting the involvement of p38 MAP kinase in the signaling of IL-4 leading to TIMP-2 expression ... The expression of the dominant negative mutant p38 MAPK represses the
IL-4 induced
TIMP-2 expression in human dermal fibroblasts
Shin et al., Rheumatology (Oxford) 2003
(Arthritis, Experimental...) :
In the serum of PG201 treated mice, the level of
TIMP-2 and the ratio of TIMP-2 to MMP-2 were significantly elevated, and the level of
IL-4 , but not of IL-10, was
increased
Bergeron et al., Clin Exp Allergy 2003
(Asthma) :
The
effect of
IL-4 on metalloproteinase-2 ( MMP-2 ) and
tissue inhibitor of metalloproteinase-2 ( TIMP-2 ) production and gene expression was evaluated