Gene interactions and pathways from curated databases and text-mining

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CTSS — HLA-DRA

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Lankar et al., J Exp Med 2002 : The reversible downregulation of cathepsin S activity led to the transient accumulation of invariant chain-MHC class II complexes in MVBs ... A few hours after BcR engagement, cathepsin S activity increased , the p10 invariant chain disappeared, and MHC class II-peptide complexes arrived at the plasma membrane
Wiendl et al., J Neuroimmunol 2003 (Myositis) : Antigen processing and presentation in human muscle : cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies