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CRK — MAP3K5

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Galvan et al., J Biol Chem 2003 : These results indicate that IGF-IR signaling suppresses the ASK-1 mediated stimulation of JNK/p38 and the induction of programmed cell death
Hassan et al., Hepatology 2009 (Hepatitis C, Chronic...) : In addition, regulated expression of core protein in HepG2 or Huh7 cells was found to induce expression and activation of the transcription factor E2F1 and apoptosis signal regulating kinase 1 ( ASK1 ), activation of c-jun-N-terminal kinase ( JNK ) and p38 , and extracellular regulated kinase (ERK), and transcription factors activator protein 1 (AP-1), activating transcription factor 2 ( ATF-2 ), cyclic adenosine monophosphate response element binding ( CREB ), E2F1, hypoxia inducing factor 1 alpha ( HIF-1alpha ), and specificity protein 1