Gene interactions and pathways from curated databases and text-mining

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CSF2 — HMGB1

Text-mined interactions from Literome

Xiang et al., Shock 2012 (Shock, Hemorrhagic) : In this study, we investigated the mechanism of HS/R regulation of HPC mobilization from BM. Using a mouse HS/R model, we demonstrate that the endogenous alarmin molecule high-mobility group box 1 mediates HS/R induced granulocyte colony stimulating factor secretion from macrophages ( M? in a RAGE [ receptor for advanced glycation end products ] signaling dependent manner
Himes et al., Immunity 1996 : Expression of HMG I or c-Rel antisense RNA inhibited CD28 activation of the IL-2 and GM-CSF promoters, implying that HMG I(Y) enhancement of c-Rel binding plays an important role in the activity of the CD28REs