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LANCL1 — TLR2
Text-mined interactions from Literome
Akamine et al., Infect Immun 2005
:
Treatment of L. pneumophila sonicated lysate with proteinase K and heating did not abolish
TLR2 dependent
IL-12p40 production
Chandra et al., Clin Exp Immunol 2008
(Leishmaniasis, Visceral...) :
In addition parasite structural integrity but not viability was required for suppression of
TLR2 stimulated
IL-12p40 and activation of IL-10
Matsushita et al., Nature 2009
(Anemia...) :
Macrophages from Zc3h12a ( -/- ) mice showed highly increased production of interleukin (IL)-6 and
IL-12p40 ( also known as IL12b ), but not TNF, in
response to
TLR ligands
McBerry et al., J Immunol 2012
(Disease Models, Animal...) :
p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed
TLR induced
IL-12/23p40 production