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CPOX — TGFB1

Text-mined interactions from Literome

Fong et al., Am J Physiol Lung Cell Mol Physiol 2000 : TGF-beta1 stimulates IL-8 release, COX-2 expression, and PGE ( 2 ) release in human airway smooth muscle cells ... In this study, we tested the ability of transforming growth factor (TGF)-beta1 to stimulate IL-8 release, cyclooxygenase (COX)-2 expression and PGE ( 2 ) generation in cultured human ASM cells and explored the role of COX products and COX-2 induction on IL-8 release
Keerthisingam et al., Am J Pathol 2001 (Pulmonary Fibrosis) : In this study we examined the effect of TGF-beta(1) on PGE ( 2 ) synthesis, proliferation, collagen production, and cyclooxygenase (COX) mRNA levels in fibroblasts derived from fibrotic and nonfibrotic human lung
Tian et al., FASEB J 2010 (Cell Transformation, Neoplastic...) : The molecular mechanisms that enable cyclooxygenase-2 (COX-2) and its mediator prostaglandin E2 ( PGE2 ) to inhibit transforming growth factor-beta ( TGF-beta ) signaling during mammary tumorigenesis remain unknown
Luo et al., J Neurochem 1998 : COX1 was increased by TGFbeta1 , but only in astrocytes ... TGFbeta1 increased COX2 expression in astrocytes and neurons
Takahashi et al., Am J Physiol 1998 (Stomach Ulcer) : In contrast, COX-2 mRNA expression and PGE2 production were promoted by prevention of TGF-beta1 action
Levi et al., Biochimie 1998 : On the other hand, COX-2 expression was up-regulated by the macrophage deactivating cytokine TGF-beta 1 , by exogenous PGE2 itself, which acted through EP2 receptors linked to cyclic AMP generation, and by non steroidal anti-inflammatory drugs