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INS — RASA1

Text-mined interactions from Literome

Noguchi et al., EMBO J 1999 : In contrast, a mutant Dok ( DokY361F ), in which Tyr361 was replaced by phenylalanine, failed to bind NCK but partially retained the ability to bind rasGAP in response to insulin
Sano et al., J Biol Chem 2003 : Insulin stimulated phosphorylation of a Rab GTPase activating protein regulates GLUT4 translocation
Porras et al., J Biol Chem 1992 : Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase activating protein phosphorylation
Wright et al., Exp Cell Res 2013 : Gap27 increased scrape-wound closure in normal glucose and insulin ( NGI ) and to a lesser extent in high glucose and insulin ( HGI )
Cullen et al., Nature 1995 : In vitro it shows GAP activity against both Rap and Ras, but only the Ras GAP activity is inhibited by phospholipids and is specifically stimulated by Ins ( 1,3,4,5 ) P4
Ogawa et al., Endocrinology 1995 (Liver Neoplasms, Experimental...) : These results indicate that both PMA and insulin can equally stimulate in FAO cells the tyrosine phosphorylation of p60 and its association with GAP , although these two agents seem to act via different signaling systems
Draznin et al., J Biol Chem 1993 : Insulin did not lead to GAP phosphorylation, or a change in cellular GAP activity, but did result in marked stimulation of Ras guanine nucleotide releasing factor ( GRF ) activity ( by 48 % in HIRc, 71 % in delta CT, and 120 % in Y/F2 cells )
DePaolo et al., Mol Cell Biol 1996 : Inhibition of PI 3-kinase activity by LY294002 or wortmannin significantly enhanced basal and insulin stimulated GTPase activating protein (GAP) activity in 3T3-L1 adipocytes