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CRP — STAT3

Pathways - manually collected, often from reviews:

• NCI Pathway Database IL6-mediated signaling events: STAT3 (dimer ) complex (STAT3) → CRP (CRP) (transcription, activates) Zhang et al., J Biol Chem 1996*
  Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Ochrietor et al., Cytokine 2000 : Role of STAT3 and C/EBP in cytokine dependent expression of the mouse serum amyloid P-component (SAP) and C-reactive protein (CRP) genes ... The results indicate that both STAT3 and C/EBPbeta participate in mouse SAP gene expression, whereas only STAT3 is involved in mouse CRP gene expression
Nishikawa et al., J Immunol 2008 : In the early induction phase, IL-1 inhibited IL-6 mediated CRP gene expression, and NF-kappaB p65 inhibited the luciferase activity of pGL3-CRP by IL-1 plus IL-6 even in the presence of overexpressed STAT3
Sun et al., Mol Cell Biochem 2011 : Phosphorylated STAT3 then activates CRP gene transcription