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SGCG — TNF
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Blalock et al., Invest Ophthalmol Vis Sci 2008
:
Neutrophil elastase and
TNF , present in higher amounts in the tears of patients with dry eye, may
cause MAM release, allowing rose bengal staining
al-Daccak et al., Infect Immun 1994
(Arthritis, Infectious...) :
In the present study, we have examined the ability of
MAM to
induce proinflammatory monokine ( interleukin 1 beta [IL-1 beta ] and tumor necrosis factor alpha
[TNF-alpha ] ) gene expression in the THP-1 monocytic cell line ... Stimulation of the U937 monocytic cell line ( MHC class II-negative even after INF-gamma treatment ) with
MAM did not
induce either IL-1 beta or
TNF-alpha transcription ... Finally, our results, obtained with protein tyrosine kinase inhibitors and antiphosphotyrosine Western blotting ( immunoblotting ), indicate that protein tyrosine kinase is involved in
MAM induced IL-1 beta and
TNF-alpha gene expression in the THP-1 monocytic cell line